Michael Boutros, Amy A. Kiger, Susan Armknecht, Kim Kerr, Marc Hild, Britta Koch, Stefan A. Haas, Heidelberg Fly Array Consortium, Renato Paro, and Norbert Perrimon

Supporting online material

Figure S1: Experimental approach for genome-wide RNAi screens.
Figure S2: Independent genome-wide RNAi screens show highly reproducible phenotypes.
Figure S3: RNAi against ribosomal genes show similar quantitative phenotypes.
Figure S4: CG15455 is a homolog of mammalian acute-myeloid leukaemia transcription factor family.
Figure S5: Cell cycle profiles associated with CG11700 and CG15455 severe RNAi phenotypes.
Figure S6: Genes identified with severe cell viability defects exhibit ectopic reaper expression.
Figure S7: Conservation of Gene products associated with Drosophila cell viability phenotypes.
Figure S8: Phenotypic distribution associated with conserved and animal-specific homologs.

Table S1: Genes identified by 438 dsRNA-induced cell growth and viability phenotypes.
Table S2: Chromosomal distribution of genes, dsRNAs and phenotypic hits.
Table S3: Genes identified by RNAi phenotypes with associated Drosophila alleles.
Table S4: Functional groups classified by InterPro domain prediction.
Table S5: Orthologs and Homologs of cell growth and viability hits.
Table S6: Human disease homologs of Drosophila genes with RNAi phenotypes.

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